Title:
【発明の名称】血清パラオキソナーゼ
Document Type and Number:
Japanese Patent JPH10502255
Kind Code:
A
Abstract:
Human serum paraoxonase enzyme and DNA (RNA) encoding such serum paraoxonase enzymes are disclosed. Also provided is the procedure for producing such polypeptides by recombinant techniques. Uses of such polypeptides include their use as an antidote for organophosphate poisoning and to prevent neuronal cell death. Diagnostic assays for identifying mutations in a nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention are also disclosed.
Inventors:
Hudson, Peter El
Fee, Way Woo
Ruben, Stephen M
Fee, Way Woo
Ruben, Stephen M
Application Number:
JP50390496A
Publication Date:
March 03, 1998
Filing Date:
June 28, 1995
Export Citation:
Assignee:
HUMAN GENOME SCIENCES, INC.
International Classes:
A61K38/46; A61P39/00; A61P43/00; C07K14/47; C12N15/09; C07K16/18; C07K16/40; C12N1/21; C12N5/06; C12N5/10; C12N9/16; C12N9/18; C12N15/12; C12N15/55; C12P21/02; C12P21/04; G01N33/53; G01N33/567; A61K38/00; A61K48/00; (IPC1-7): C12N15/09; C07K14/47; C07K16/18; C12N5/10; C12N9/16; C12P21/02
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)