Title:
【発明の名称】動物細胞において遺伝子を導入および発現させるための方法
Document Type and Number:
Japanese Patent JPH11505219
Kind Code:
A
Abstract:
A method for introducing and expressing genes in animal cells is disclosed comprising infecting said animal cells with live invasive bacteria, wherein said bacteria contain a eukaryotic expression cassette encoding said gene. The gene may encode, e.g., a vaccine antigen, an therapeutic agent, an immunoregulatory agent or a anti-sense RNA or a catalytic RNA.
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Inventors:
Powell, Robert Jay.
Rewys, George Kay.
Horn, David M.
Rewys, George Kay.
Horn, David M.
Application Number:
JP53332996A
Publication Date:
May 18, 1999
Filing Date:
April 24, 1996
Export Citation:
Assignee:
University of Maryland at Baltimore
International Classes:
C12N15/09; A61K35/74; A61K39/00; A61K45/00; A61K48/00; A61P31/04; A61P31/12; A61P33/00; C12N1/21; C12N5/10; C12N15/87; (IPC1-7): A61K48/00; A61K35/74; A61K39/00; A61K45/00; A61K48/00; C12N15/09
Attorney, Agent or Firm:
Shusaku Yamamoto