Title:
【発明の名称】成長ホルモン分泌促進剤の製造方法
Document Type and Number:
Japanese Patent JPH11513984
Kind Code:
A
Abstract:
The present invention is directed to a novel process for the preparation of the compound N-[1(R)-[(1,2-dihydro-1-methanesulfonyl-spiro[3H-indole-3,4'-piperdin]-1'-yl)carbonyl]-2-(phenylmethyl-oxy)ethyl]-2-amino-2-methyl-propanamide, and salts thereof, which has structure (1) and which has the ability to stimulate the release of natural or endogenous growth hormone. This compound may be used to treat conditions which require the stimulation of growth hormone production or secretion such as in humans with a deficiency of natural growth hormone or in animals used for food or wool production where the stimulation of growth hormone will result in a larger, more productive animal.
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Inventors:
Houghton, Peter G
Hopis, Ioannis
Molina, Audrey
Lynch, Youjiu Yi
Borant, Ralph Pee
Hopis, Ioannis
Molina, Audrey
Lynch, Youjiu Yi
Borant, Ralph Pee
Application Number:
JP51673697A
Publication Date:
November 30, 1999
Filing Date:
October 23, 1996
Export Citation:
Assignee:
Merck End Company, Inc.
International Classes:
C07D471/10; C07K5/06; C07K5/062; A61K38/00; (IPC1-7): C07D471/10
Attorney, Agent or Firm:
Yoshio Kawaguchi (1 person outside)