Document Type and Number:
Japanese Patent JPS4929076
Kind Code:
B1
Abstract:
The invention relates to a process for the preparation of 7 beta -acylamido-3-methylceph-3-em-4-carboxylic acid esters from compounds of the penicillin type, in particular, 6 beta -acylamido penicillanic acid 1-oxide esters, in the presence of a catalyst selected from a mono-O-substituted orthophosphoric acid, an 0,0-di(aryl substituted) orthophosphoric acid, a salt or complex formed from a nitrogen base having a pKb of not less than 4 and a mono-0-substituted orthophosphoric acid or an 0,0-di(aryl substituted) orthophosphoric acid. The salt or complex may be formed in situ in the reaction mixture.
Application Number:
JP4556072A
Publication Date:
August 01, 1974
Filing Date:
May 10, 1972
Export Citation:
International Classes:
C07D501/04; A61K31/545; B01J31/02; C07D501/10; C07D501/22; C07F9/12; (IPC1-7): C07F9/58