Title:
ペプチド誘導体及びその薬学的に許容される塩、その製造法並びにその用途
Document Type and Number:
Japanese Patent JPWO2003042237
Kind Code:
A1
Abstract:
The present invention provides a peptide derivative of formula (I) or a pharmaceutically acceptable salt thereof wherein X is -CH(OH)- or -CO-; R<1> is hydrogen or an amino protecting group; R<2> is hydroxyl or lower alkoxy; one of R<3> and R<4> is the side chain (R group) of lysine the amino group of which may be protected with a protecting group and the other of R<3> and R<4> is the side chain (R group) of arginine the guanidino group of which may be protected with a protecting group; and R<5> and R<6> may be the same or different and are hydrogen, lower alkyl or aralkyl. The present invention further provides a production process and use thereof.
Inventors:
山本 健二
須田 悦光
浅尾 哲次
須田 悦光
浅尾 哲次
Application Number:
JP2003544072A
Publication Date:
March 10, 2005
Filing Date:
November 14, 2002
Export Citation:
Assignee:
大鵬薬品工業株式会社
International Classes:
C07K5/023; A61K38/00; A61K38/55; A61P1/02; A61P43/00; C07C279/36; C07K5/02; C12N9/99