Title:
４−メトキシメチル−２，３，５，６−テトラフルオロベンゼンメタノールの合成方法
Document Type and Number:
Japanese Patent JP6942930
Kind Code:
B2
Abstract:
The disclosure discloses a method for synthesizing 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol from 1,4-bis(methoxymethyl)-2,3,5,6-tetrafluorobenzene, belongings to the technical field of organic synthesis. 1,4-bis(methoxymethyl)-2,3,5,6-tetrafluorobenzene reacts in mixed solution consisting of sulfuric acid aqueous solution and organic carboxylic acid, the obtained mixture is subjected to ester group hydrolysis reaction in the presence of an inorganic base and then to hydroxyl methylation reaction, 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol is finally obtained via separation and purification, and 1,4-bis(methoxymethyl)-2,3,5,6-tetrafluorobenzene is recovered. The disclosure not only realizes the resource utilization of low-value 1,4-bis(methoxymethyl)-2,3,5,6-tetrafluorobenzene, and meanwhile has the advantages of mild reaction conditions, simple operation, high synthesis yield, good product quality and the like. The disclosure has high social and economic values.
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Inventors:
Go Sosuke
Zhang Keitoku
Chen Haifeng
崔毅▲きん▼
Chen Toraho
Super king
Zhang Keitoku
Chen Haifeng
崔毅▲きん▼
Chen Toraho
Super king
Application Number:
JP2020568014A
Publication Date:
September 29, 2021
Filing Date:
January 18, 2019
Export Citation:
Assignee:
浙江中欣▲ふう▼材股▲ふん▼有限公司
International Classes:
C07C41/16; C07C41/42; C07C43/178
Domestic Patent References:
| JP2001220360A | ||||
| JP57123146A |
Foreign References:
| CN107089904A |
Attorney, Agent or Firm:
Koji Tsubouchi