Title:
びまん性大細胞型Ｂ細胞リンパ腫を治療するための５－フルオロ－４－（４－フルオロ－２－メトキシフェニル）－Ｎ－｛４－［（Ｓ－メチルスルホンイミドイル）メチル］ピリジン－２－イル｝ピリジン－２－アミンの使用
Document Type and Number:
Japanese Patent JP7280286
Kind Code:
B2
Abstract:
The present invention relates to the use of 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine (compound A), more particularly (+)5-Fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine (compound A′), for treating diffuse large B-cell lymphoma (DLBCL), especially in germinal-centre B-cell type of diffuse large B-cell lymphoma and especially in diffuse large B-cell lymphoma which cells have an amplification or translocation of the MYC gene and/or BCL2 gene and/or an overexpression of MYC and/or BCL2.
Inventors:
Arne Scholz
Application Number:
JP2020565543A
Publication Date:
May 23, 2023
Filing Date:
February 12, 2019
Export Citation:
Assignee:
Bayer Aktiengesellschaft
International Classes:
A61K31/444; A61K31/44; A61K45/00; A61P35/00; A61P43/00; C07D213/74
Domestic Patent References:
| JP2015537015A |
Other References:
Blood,2016年,Vol. 128, Issue 22, No. 289
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mihiro
Tatsuhiko Abe
Shinya Mihiro
Tatsuhiko Abe
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