Title:
免疫刺激因子トル様受容体７（ＴＬＲ７）アゴニストとしての６－アミノ―７，９－ジヒドロ－８Ｈ－プリン－８－オン誘導体
Document Type and Number:
Japanese Patent JP7228571
Kind Code:
B2
Abstract:
where R1, R2, and Ar are as defined herein, are agonists for the Toll-like receptor 7 (TLR7) and can be used as adjuvants for stimulating the immune system. Some such compounds can be used in conjugates for targeted delivery to the organ or tissue of intended action.
Inventors:
Lychee He
Sanjeev Gang War
Shoshana El Posey
Yam Bee Poudel
Prasanna Shiva Prakasam
Sanjeev Gang War
Shoshana El Posey
Yam Bee Poudel
Prasanna Shiva Prakasam
Application Number:
JP2020509076A
Publication Date:
February 24, 2023
Filing Date:
August 16, 2018
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07D473/18
Domestic Patent References:
| JP2013508373A | ||||
| JP2014531231A | ||||
| JP2009528989A |
Foreign References:
| WO2008114817A1 |
Attorney, Agent or Firm:
Yamato Kento
Shinagawa
Futami Kamahira
Masahiro Suwon
Wu Yingyan
Shinagawa
Futami Kamahira
Masahiro Suwon
Wu Yingyan