Title:
7 TRANSMEMBRANE RECEPTOR PROTEIN ET 60
Document Type and Number:
Japanese Patent JPH11155573
Kind Code:
A
Abstract:
To provide the subject protein effective for controlling the function of leukocyte, especially autoreactive T cell and useful for searching medicine for controlling the disease.
This protein is a 7 transmimbrane receptor protein ET 60 or its salt containing an amino acid sequence essentially same at the amino acid sequence of the formula. It can be prepared by collecting a cDNA fragment of the 7 transmembrane receptor protein ET 60 from autoreactive T cell 4R312 strain causing the crisis of experimental allergic encephalomyelitis(EAE), collecting its cDNA coding region over the whole length, preparing an expression system of a protein encoded by the cDNA and allowing the cell membrane of the transformant to produce the subject protein.
Inventors:
ISHIMARU HIROSHI
IEMURA NAOKO
KOSHIO TAKEHIRO
IEMURA NAOKO
KOSHIO TAKEHIRO
Application Number:
JP32582397A
Publication Date:
June 15, 1999
Filing Date:
November 27, 1997
Export Citation:
Assignee:
ASAHI CHEMICAL IND
International Classes:
G01N33/566; C07K14/705; C07K16/28; C12N5/10; C12N15/09; C12P21/02; (IPC1-7): C12N15/09; C07K14/705; C07K16/28; C12N5/10; C12P21/02; G01N33/566