Title:
ACYLPEPTIDE* ITS MANUFACTURE AND MEDICINAL MEDICINE CONTAINING IT
Document Type and Number:
Japanese Patent JPS5692850
Kind Code:
A
Abstract:
Acylpeptides derived from somatostatin or from a derivative thereof having analogous action, in which the amino acids sequence is modified by omitting individual amino acids and/or by exchanging them for other amino acids, and in which the epsilon -amino group of the lysine residue in the 9-position, and optionally also the epsilon -amino group of the lysine residue in the 4-position and/or the N-terminal alpha -amino group carries the acyl radical of an optionally substituted alkanecarboxylic acid, and salts and complexes thereof can be used as antidiabetics and/or for combating gastrointestinal bleeding. They are manufactured by conventional methods of peptide chemistry.
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Inventors:
HANSU RINKU
PEETAA SHIIBAA
BURUNO KANBAA
PEETAA SHIIBAA
BURUNO KANBAA
Application Number:
JP17474980A
Publication Date:
July 27, 1981
Filing Date:
December 12, 1980
Export Citation:
Assignee:
CIBA GEIGY AG
International Classes:
A61K38/04; A61P43/00; C07K14/575; C07C67/00; C07C231/00; C07C231/02; C07K1/06; C07K1/107; C07K1/113; C07K7/00; C07K14/655; A61K38/00; (IPC1-7): A61K37/02; C07C102/00; C07C103/52
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