Title:
AGENT FOR PROMOTING EXPRESSION OF N-ACETYLGALACTOSAMINYLTRANSFERASE CONTAINING EXTRACT FROM INFLAMED TISSUES INOCULATED WITH VACCINIA VIRUS
Document Type and Number:
Japanese Patent JP2019142853
Kind Code:
A
Abstract:
To provide, e.g., an agent for promoting expression of N-acetylgalactosaminyltransferase that contains an extract from inflamed tissues inoculated with the vaccinia virus.SOLUTION: The present invention demonstrated that the extract from inflamed tissues inoculated with the vaccinia virus promotes the expression of N-acetylgalactosaminyltransferase in intervertebral disc cells. Thus, the extract from inflamed tissues inoculated with the vaccinia virus or a preparation containing the extract is useful, e.g., as an agent for promoting the expression of N-acetylgalactosaminyltransferase in intervertebral disc cells.SELECTED DRAWING: Figure 1
Inventors:
SAKAI DAISUKE
NAKAI TOMOKO
UCHIKI MITSURU
SHIBAYAMA YOJI
NAKAI TOMOKO
UCHIKI MITSURU
SHIBAYAMA YOJI
Application Number:
JP2019027686A
Publication Date:
August 29, 2019
Filing Date:
February 19, 2019
Export Citation:
Assignee:
UNIV TOKAI
NIPPON ZOKI PHARMACEUTICAL CO
NIPPON ZOKI PHARMACEUTICAL CO
International Classes:
A61K35/76; A61K9/06; A61K9/08; A61K35/36; A61K47/02; A61P25/00; A61P43/00; C12Q1/02; C12Q1/6837; C12Q1/6851; C12Q1/686
Domestic Patent References:
| JP2013544785A | 2013-12-19 | |||
| JP2007254455A | 2007-10-04 |
Other References:
生化学, 2017, VOL.89 NO.2, P.259-263, JPN6022054415, ISSN: 0005110181
JBC., 2007, VOL.282 NO.6, P.4152-4161, JPN6022054416, ISSN: 0005110182
日薬理誌, 1990, VOL.96, P.153-161, JPN6022054417, ISSN: 0004956814
JBC., 2007, VOL.282 NO.6, P.4152-4161, JPN6022054416, ISSN: 0005110182
日薬理誌, 1990, VOL.96, P.153-161, JPN6022054417, ISSN: 0004956814
Attorney, Agent or Firm:
Ikuo Fujii