PURPOSE: To obtain an agent for treating skin itchiness, especially an agent effective against skin itchiness of the patient of chronic renal failure (especially patient subjected to maintenance dialysis) and aged person by using a fat emulsion known as a nutrient infusion for medical use.

CONSTITUTION: The objective agent for the treatment of skin itchiness is composed of a fat emulsion (especially preferably an O/W-type emulsion) obtained by properly adding an emulsifying assistant to a mixture of an oil component (e.g. soybean oil), a nonionic surfactant, an emulsifier (e.g. phospholipid) and water. The fat emulsion has an O/W-type structure in general and, in this case, the particle diameter is preferably ≤1μm. The agent is administered by parenteral administration (e.g. injection), especially by intravenous injection (injection to the vein-side of the dialysis circuit in the case of a patient of maintenance dialysis). The fat emulsion of 5-30% concentration is administered in an amount of 100-1,000ml once a day or 1-4 times a week.