Title:
ANALGESIC NOVEL COMPOUND AND COMPOSITION
Document Type and Number:
Japanese Patent JPS6084251
Kind Code:
A
Abstract:
Alkynamide compounds, and pharmaceutically-acceptable salts thereof, of the formula: wherein X is O or S; R is straight or branched alkyne having from 11 to 23 carbon atoms; R1 is H, OH, or OCH3; R2 is OH or a short-chain ester; and wherein at least one of R1 and R2 is OH or OCH3. Compositions, useful for producing analgesia in humans or lower animals, comprise a safe and effective amount of: an alkynamide, pharmaceutically-acceptable salts thereof, or mixtures thereof; and a pharmaceutically-acceptable carrier. Preferably, these alkynamides are N-vanillyl-alkynamides. Methods of treatment, comprising administering a safe and effective amount of these alkynamides, pharmaceutically-acceptable salts thereof, or mixtures thereof, include methods of parenteral, oral, and topical administration.
Inventors:
JIYON MAIKURU YAANUSU
TOMASU ROBAATO RAHAN
TOMASU ROBAATO RAHAN
Application Number:
JP14586084A
Publication Date:
May 13, 1985
Filing Date:
July 13, 1984
Export Citation:
Assignee:
PROCTER & GAMBLE
International Classes:
A61K31/165; A61K31/22; A61P25/04; C07C67/00; C07C233/16; C07C233/18; C07C233/20; C07C325/00; C07C327/40; C07C327/42; (IPC1-7): A61K31/165; C07C103/60; C07C153/063
Attorney, Agent or Firm:
Kiyoshi Inomata (3 outside)