Title:
抗-CD28抗体
Document Type and Number:
Japanese Patent JP4066166
Kind Code:
B2
Abstract:
An antibody or antibody fragment directed against the CD28 receptor which blocks the interaction between B7-1 or B7-2 and CD28. Methods for blocking activation via CD28, including CD28-dependent lymphocyte activation.
Inventors:
Sourirou, Jean-Paul
Rafranme, Genevieve
Van Hove, Bernardo
Olive daniel
Rafranme, Genevieve
Van Hove, Bernardo
Olive daniel
Application Number:
JP2002552964A
Publication Date:
March 26, 2008
Filing Date:
December 26, 2001
Export Citation:
Assignee:
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE(INSERM)
International Classes:
C12N15/09; A61K38/00; A61K39/395; A61P29/00; A61P37/06; A61P37/08; C07K16/28; C07K16/46; C07K19/00; C12N5/10; C12P21/02
Domestic Patent References:
| JP4502009A |
Foreign References:
| WO1997007671A1 |
Other References:
International Immunology,1993年,Vol.5, No.3,pp.311-315
Tissue Antigens,1996年,Vol.47,pp.1-20
Blood,2002年,Vol.99, No.6,pp.2228-2234
J. Immunol.,1988年,Vol.140,pp.1753-1761
J. Biol. Chem.,1996年,Vol.271, No.16,pp.9403-9409
J. Immunol.,1999年, Vol.163,pp.1704-1710
Tissue Antigens,1996年,Vol.47,pp.1-20
Blood,2002年,Vol.99, No.6,pp.2228-2234
J. Immunol.,1988年,Vol.140,pp.1753-1761
J. Biol. Chem.,1996年,Vol.271, No.16,pp.9403-9409
J. Immunol.,1999年, Vol.163,pp.1704-1710
Attorney, Agent or Firm:
Shintaro Nogawa