Title:
ANTI-FAMILY WITH SEQUENCE SIMILARITY 19, MEMBER A5 ANTIBODIES AND METHOD OF USE THEREOF
Document Type and Number:
Japanese Patent JP2022002545
Kind Code:
A
Abstract:
To provide an antibody that specifically binds to human FAM19A5, and a composition including the antibody.SOLUTION: In a specific aspect, antibodies specifically bind to human FAM19A5 and modulate FAM19A5 activity, for example, inhibit, suppress, reduce, or reverse onset of reactive gliosis and/or excessive proliferation of reactive astrocytes, utilizing such antibodies. The present disclosure also provides methods for treating disorders, such as central nervous system damage, a degenerative brain disorder, or a neuropathic pain, by administering an antibody that specifically binds to human FAM19A5.SELECTED DRAWING: None
Inventors:
CHUNG JUNHO
YUNE TAE YOUNG
KIM BONGCHEOL
SEONG JAE YOUNG
HWANG JONG IK
JIN JUNYEONG
LEE JEE YOUN
CHO EUN BEE
YUNE TAE YOUNG
KIM BONGCHEOL
SEONG JAE YOUNG
HWANG JONG IK
JIN JUNYEONG
LEE JEE YOUN
CHO EUN BEE
Application Number:
JP2021170509A
Publication Date:
January 11, 2022
Filing Date:
October 18, 2021
Export Citation:
Assignee:
NEURACLE SCIENCE CO LTD
International Classes:
C12N15/13; A61K39/395; A61P25/00; C07K16/18
Domestic Patent References:
| JP7045724B2 | 2022-04-01 |
Foreign References:
| EP2815769A1 | 2014-12-24 |
Attorney, Agent or Firm:
Creation International Patent Office