Title:
炎症性疾患の治療に用いる抗TIRC7抗体
Document Type and Number:
Japanese Patent JP2005531282
Kind Code:
A
Abstract:
A method for the treatment of inflammatory disorders is disclosed, particularly the treatment of arthritis. The method comprises particular therapeutic and preventive treatment regimens for the administration of a T-cell immune response cDNA 7 (TIRC7) antagonist, preferably an anti-TIRC7 antibody. Particularly useful monoclonal, in particular chimeric anti-TIRC7 antibodies are described. Furthermore, a combination therapy for the treatment of an inflammatory disease, particularly rheumatoid arthritis, is provided involving the use of TIRC7 antagonist, such as anti-TIRC7 antibody in conjunction with an anti-inflammatory drug such as TNF-α antagonist.
Inventors:
Utuk, Naran
Application Number:
JP2003554734A
Publication Date:
October 20, 2005
Filing Date:
December 23, 2002
Export Citation:
Assignee:
GENPAT77 PHARMACOGENETICS AG
International Classes:
A61K31/7088; A61K39/395; A61K45/00; A61K45/06; A61P19/02; A61P29/00; A61P43/00; C07K16/24; C07K16/28; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/13; (IPC1-7): C12N15/09; A61K31/7088; A61K39/395; A61K45/00; A61K45/06; A61P19/02; A61P29/00; A61P43/00; C07K16/24; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10
Attorney, Agent or Firm:
Tomimasa Konishi
Tomoko Nakamura
Mikiharu Hagino
Tomoko Nakamura
Mikiharu Hagino