Title:
クローディン３のＥＣＬ－２に特異的に結合する抗体、その断片及びその使用
Document Type and Number:
Japanese Patent JP7311530
Kind Code:
B2
Abstract:
The invention of the present application relates to a use of an antibody biding specifically to ECL-2 of claudin 3 and functional fragments thereof in cancer cell detection, diagnosis, imaging, and application to cancer treatment (anticancer use of the antibody itself, and application to ADC and CAR-expression cells (particularly immune cells)), an antibody that includes a characteristic CDR sequence exerting a remarkable effect in such uses, and a functional fragment thereof.
More Like This:
Inventors:
Shin, Young Ki
Hong, Sung Yul
Kim, Young Dog
Choi, Jun Young
Yang, Ho Bin
Park, Ha Young
Kim, Sung Soo
Hong, Sung Yul
Kim, Young Dog
Choi, Jun Young
Yang, Ho Bin
Park, Ha Young
Kim, Sung Soo
Application Number:
JP2020552830A
Publication Date:
July 19, 2023
Filing Date:
March 27, 2019
Export Citation:
Assignee:
ABION INC.
International Classes:
C12N15/13; A61K39/395; A61K45/00; A61K47/68; A61P35/00; A61P35/04; C07K14/705; C07K14/725; C07K14/74; C07K16/28; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/078; C12N5/10; C12N15/12; C12N15/62; C12N15/63; C12P21/02; G01N33/53; G01N33/533; G01N33/534; G01N33/535; G01N33/543; G01N33/574
Other References:
Oncotarget,2015年09月21日,Vol.6, No.33,p34617-34628 ,https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741477/参照
Attorney, Agent or Firm:
Patent Attorney Corporation Hanabusa Patent and Trademark Office