Title:
抗マラリア性ヘキサヒドロピリミジン類似体
Document Type and Number:
Japanese Patent JP7342025
Kind Code:
B2
Abstract:
The application relates to a series of 2-imino-6-methylhexahydropyrimidin-4-one derivatives and 3-imino-5-methyl-1,2,4-thiadiazinane 1,1-dioxide derivatives of formula (I), substituted by an arylaminophenyl or heteroarylaminophenyl moiety. The compounds are potent inhibitors of the growth and propagation of the Plasmodium falciparum parasite in human blood and thus useful as pharmaceutical agents for the treatment of malaria.
Inventors:
De Haro Garcia, Teresa
King, Lloyd Malcolm
Rowe, Martin Aligander
McCos, Malcolm
Taylor, Richard David
Chu, Chaonin
King, Lloyd Malcolm
Rowe, Martin Aligander
McCos, Malcolm
Taylor, Richard David
Chu, Chaonin
Application Number:
JP2020554487A
Publication Date:
September 11, 2023
Filing Date:
April 02, 2019
Export Citation:
Assignee:
UCB Biopharma SRL
International Classes:
C07D239/22; A61K31/513; A61K31/5377; A61K31/538; A61P33/06; C07D239/42; C07D401/12; C07D403/06; C07D403/12; C07D405/04; C07D405/14; C07D413/14; C07D471/04; C07D493/08
Domestic Patent References:
| JP2013507368A |
Foreign References:
| WO2016172255A1 | ||||
| WO2016118404A1 | ||||
| WO2017144517A1 | ||||
| WO2017089453A1 |
Attorney, Agent or Firm:
Patent Attorney Corporation Asamura Patent Office
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