Title:
Antisense regulation of PTP1B revelation
Document Type and Number:
Japanese Patent JP5951752
Kind Code:
B2
Abstract:
Provided herein are methods, compounds, and compositions for reducing expression of PTP1B mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate metabolic disease, for example, diabetes, or a symptom thereof.
Inventors:
Bannot, Sanjay
Flair, Susan M
Flair, Susan M
Application Number:
JP2014505350A
Publication Date:
July 13, 2016
Filing Date:
April 13, 2012
Export Citation:
Assignee:
Ionis Pharmaceuticals,Inc.
International Classes:
C12N15/113; A61K31/7088; A61K31/7115; A61K31/712; A61K31/7125; A61K48/00; A61P3/04; A61P3/10; A61P43/00
Domestic Patent References:
| JP2004535179A | ||||
| JP2003523739A |
Foreign References:
| WO2008109470A1 | ||||
| US20100197773 |
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Shigeo Takeuchi
Osamu Yamamoto
Norihiro Fukasawa
Yasushi Kobayashi
Shigeo Takeuchi
Osamu Yamamoto
Norihiro Fukasawa