アプタマー-毒素分子およびこれを使用する方法

Title:

アプタマー-毒素分子およびこれを使用する方法

Document Type and Number:

Japanese Patent JP2005533794

Kind Code:

A

Abstract:

Materials and methods are provided to prepare therapeutic conjugates for the treatment of proliferative diseases. The therapeutic conjugates of the invention comprise a targeting moiety conjugated to a therapeutic moiety. The therapeutic moiety of the conjugates of the present invention have a cytotoxic effect and are useful in the treatment of proliferative diseases.

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Inventors:

Stanton, Martin
Cars, Marcus

Application Number:

JP2004513472A

Publication Date:

November 10, 2005

Filing Date:

June 18, 2003

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Assignee:

Archemix Corporation

International Classes:

A61K38/00; A61K47/48; A61K51/00; A61P35/00; A61P43/00; C12N15/115; C12Q1/68; (IPC1-7): A61K38/00; A61K51/00; A61P35/00; A61P43/00

Attorney, Agent or Firm:

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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