ARYL ANILINE 2 ADRENERGIC RECEPTOR AGONIST

Japanese Patent JP2009167199

A

To provide a 2 adrenergic receptor agonist with improved characteristics.

The adrenergic receptor agonist compound is represented by the formula. A pharmaceutical composition comprising the compound, a method of using the compound to treat diseases associated with 2 adrenergic receptor activity, and a method and an intermediate useful for preparing the compound are also provided.

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MORAN EDMUND J
JACOBSEN JOHN R
LEADBETTER MICHAEL R
NODWELL MATTHEW B
TRAPP SEAN G
AGGEN JAMES
CHURCH TIMOTHY J

JP2009063650A

July 30, 2009

March 16, 2009

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THERAVANCE INC

C07C311/44; A61K31/136; C07D295/22; A61K31/137; A61K31/145; A61K31/16; A61K31/167; A61K31/18; A61K31/245; A61K31/352; A61K31/357; A61K31/366; A61K31/4152; A61K31/426; A61K31/4402; A61K31/4453; A61K31/4704; A61K31/4709; A61K31/505; A61K31/5375; A61K31/5377; A61K31/63; A61K31/635; A61K45/00; A61P9/00; A61P11/00; A61P11/06; A61P15/06; A61P25/00; A61P29/00; A61P43/00; C07C215/60; C07C215/82; C07C217/84; C07C217/86; C07C217/92; C07C229/38; C07C229/60; C07C233/43; C07C317/36; C07C323/36; C07C323/37; C07D213/75; C07D213/76; C07D215/227; C07D215/26; C07D231/20; C07D231/22; C07D239/38; C07D239/42; C07D239/46; C07D239/47; C07D277/20; C07D277/46; C07D277/52; C07D311/80; C07D319/18; C07D321/10; C07D401/12; C07D405/12; C07D409/12; C07D413/12; C07D215/22

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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