Title:
弱毒ヒト-ウシキメラ-パラインフルエンザウイルス(PIV)ワクチン
Document Type and Number:
Japanese Patent JP4813711
Kind Code:
B2
Abstract:
Chimeric human-bovine parainfluenza viruses (PIVs) are infectious and attenuated in humans and other mammals and useful individually or in combination in vaccine formulations for eliciting an anti-PIV immune response. Also provided are isolated polynucleotide molecules and vectors incorporating a chimeric PIV genome or antigenome which includes a partial or complete human or bovine PIV "background" genome or antigenome combined or integrated with one or more heterologous gene(s) or genome segment(s) of a different PIV.
Inventors:
Schmidt, Alexander Sea
Skiadopoulos, Mario H
Collins, Peter El
Murphy, Brian Earle
Bailey, Gene Yee
Durbin, Anna Pee
Skiadopoulos, Mario H
Collins, Peter El
Murphy, Brian Earle
Bailey, Gene Yee
Durbin, Anna Pee
Application Number:
JP2001509524A
Publication Date:
November 09, 2011
Filing Date:
June 16, 2000
Export Citation:
Assignee:
THE UNITED STATES OF AMERICA
International Classes:
C12N15/09; A61K9/12; A61K39/145; A61P31/16; C07K14/115; C12N7/00; C12N7/04; C12N15/45; C12R1/93
Foreign References:
| WO1997020468A1 | 1997-06-12 | |||
| WO1998053078A1 | 1998-11-26 |
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri