Title:
Autogenous control discharge of an active medicine ingredient
Document Type and Number:
Japanese Patent JP6027283
Kind Code:
B2
Abstract:
The present invention relates to an abuse deterrent pharmaceutical composition comprising:
a. a pharmaceutically active ingredient;
b. an acid soluble ingredient comprising one or more of calcium carbonate, dibasic calcium phosphate, tribasic calcium phosphate, and magnesium hydroxide; and
c. a buffering ingredient;
wherein the acid soluble component is included in the form of a particle matrix with the active pharmaceutical ingredient,
wherein the buffering ingredient is present in an amount sufficient to inhibit dissolution of the particle matrix when the abuse deterrent pharmaceutical composition is ingested in an excess amount.
Inventors:
Brzeczech, Albert W
Hollenbeck, Gary Earl
Hollenbeck, Gary Earl
Application Number:
JP2016080783A
Publication Date:
November 16, 2016
Filing Date:
April 14, 2016
Export Citation:
Assignee:
Acura Pharmaceuticals Incorporated
International Classes:
A61K47/32; A61K45/00; A61K47/02; A61P25/00; A61P25/04; A61P25/30
Foreign References:
| WO2011121824A1 |
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Shigeo Takeuchi
Osamu Yamamoto
Naoshi Nakata
Yasushi Kobayashi
Shigeo Takeuchi
Osamu Yamamoto
Naoshi Nakata
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