Title:
BENZALDEHYDE DERIVATIVE AND ITS MANUFACTURE
Document Type and Number:
Japanese Patent JPS56154429
Kind Code:
A
Abstract:
The invention provides the novel chemical intermediate 4-(4-chlorophenyl)benzaldehyde, or the hydrate thereof; processes for its production and for its conversion to the known compounds 4-(4-chlorophenyl)-benzyl alcohol and 4-(4-chlorophenyl)benzyl chloride and bromide. These latter compounds are intermediates known for use in the manufacture of anti-arthritic benzyloxyacetic acids of the formula: in which Re is hydrogen or (1-4C)alkyl and Rf is (1-4C)alkyl or phenyl optionally bearing a halogeno substituent, and have previously only been obtainable by the use of potentially toxic chloromethyl ethers. The invention therefore also provides processes for the manufacture of the anti-arthritic acids of formula IV starting from 4-(4-chlorophenyl)benzaldehyde which avoid the use of such hazardous ethers.
More Like This:
| JP2007515408 | Practical, cost-effective synthesis of ubiquinone |
| WO/2001/060772 | PROCESS FOR PRODUCTION OF ALLYL CHLORIDE |
| WO/2006/062477 | CHEMICAL PROCESS |
Inventors:
REIMONDO AREKISANDAA BOOII
Application Number:
JP4951381A
Publication Date:
November 30, 1981
Filing Date:
April 03, 1981
Export Citation:
Assignee:
ICI LTD
International Classes:
C07C17/16; C07C29/14; C07C45/00; C07C45/49; C07C45/56; C07C69/708; C07C47/55; C07C51/00; C07C59/125; C07C59/66; C07C67/00; (IPC1-7): C07C45/49; C07C47/55; C07C59/125; C07C69/708