Title:
Benzamides And Related Inhibitors Of Factor Xa
Document Type and Number:
Japanese Patent JP4744050
Kind Code:
B2
Abstract:
Compounds of the formula A - Q - D - E - G - J - X in which D is a direct link, a substituted or unsubstituted phenyl or naphthyl group or a heterocyclic ring system; X is a substituted or unsubstituted phenyl or naphthyl group or a heterocyclic system; and the other variables are as defined in the claims, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.
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Inventors:
Tzu, Bin-Yang
Zan, Penley
Wang, Lin Yang
Wang, Wen Long
Eric, Goldman
Lee, Wenhao
Zuket, Jinmei
Song, Yong Hong
Scarborough, Robert
Zan, Penley
Wang, Lin Yang
Wang, Wen Long
Eric, Goldman
Lee, Wenhao
Zuket, Jinmei
Song, Yong Hong
Scarborough, Robert
Application Number:
JP2001523368A
Publication Date:
August 10, 2011
Filing Date:
September 15, 2000
Export Citation:
Assignee:
MILLENNIUM PHARMACEUTICALS, INC.
International Classes:
C07D213/75; A61K31/18; A61K31/44; A61K31/4427; A61K31/4439; A61K31/4545; A61K31/472; A61K31/496; A61K31/506; A61K31/5377; A61K31/541; A61K31/55; A61K31/5513; A61P7/02; A61P9/10; C07C311/16; C07C311/46; C07C317/40; C07C317/44; C07D213/81; C07D213/82; C07D217/22; C07D277/56; C07D333/38; C07D401/04; C07D401/06; C07D401/12; C07D401/14; C07D403/04; C07D403/06; C07D403/12; C07D403/14; C07D405/12; C07D409/12; C07D409/14; C07D417/04; C07D417/12; C07D417/14; C07D471/04; C07D487/04; C07D521/00
Domestic Patent References:
| JP2002533454A | ||||
| JP2002512633A | ||||
| JP2002508771A | ||||
| JP2001509145A |
Attorney, Agent or Firm:
Masatake Ide