Title:
BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS
Document Type and Number:
Japanese Patent JP2023108032
Kind Code:
A
Abstract:
To provide benzenesulfonamide compounds and their use as therapeutic agents.SOLUTION: This invention is directed to benzenesulfonamide compounds (which are compounds as stereoisomers, enantiomers or tautomers thereof or mixtures thereof), or pharmaceutically acceptable salts, solvates or prodrugs thereof, for treatment of diseases or conditions associated with voltage-gated sodium channels, such as epilepsy. Of this embodiment, a preferred compound is 4-((1-benzylazetidin-3-yl)oxy)-3-chloro-N-(thiazol-2-yl)benzene-sulfonamide.SELECTED DRAWING: None
Inventors:
JEAN-CHRISTOPHE ANDREZ
KRISTEN NICOLE BURFORD
SULTAN CHOWDHURY
CHARLES J COHEN
CHRISTOPH MARTIN DEHNHARDT
ROBERT JOSEPH DEVITA
JAMES ROY EMPFIELD
THILO FOCKEN
MICHAEL EDWARD GRIMWOOD
SYED ABID HASAN
JAMES PHILIP JOHNSON JR
ALLA YUREVNA ZENOVA
KRISTEN NICOLE BURFORD
SULTAN CHOWDHURY
CHARLES J COHEN
CHRISTOPH MARTIN DEHNHARDT
ROBERT JOSEPH DEVITA
JAMES ROY EMPFIELD
THILO FOCKEN
MICHAEL EDWARD GRIMWOOD
SYED ABID HASAN
JAMES PHILIP JOHNSON JR
ALLA YUREVNA ZENOVA
Application Number:
JP2023099277A
Publication Date:
August 03, 2023
Filing Date:
June 16, 2023
Export Citation:
Assignee:
XENON PHARMACEUTICALS INC
International Classes:
C07D401/12; A61K31/427; A61K31/437; A61K31/4439; A61K31/454; A61K31/4545; A61K31/46; A61K31/506; A61P25/08; A61P43/00; C07D413/12; C07D417/14; C07D451/02; C07D471/04
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita
Natsuki Morishita