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Title:
Biological preparation
Document Type and Number:
Japanese Patent JP5920934
Kind Code:
B2
Abstract:
There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human CD22. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a modified CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by cells expressing CD22.

Inventors:
Poppelwell, Andrew, George
Tickle, Simon, Peter
Ladyman, Heather, Margaret
Application Number:
JP2013140245A
Publication Date:
May 18, 2016
Filing Date:
July 04, 2013
Export Citation:
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Assignee:
Yusebe Pharma Societe Anonym
International Classes:
C07K16/18; C12N15/09; A61K38/16; A61K39/395; A61P35/00; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/13; C12N15/63; C12P21/00; C12P21/08
Domestic Patent References:
JP10505231A
JP2010022372A
Other References:
S. LEUNG,MOLECULAR IMMUNOLOGY,英国,1995年12月,V32 N17/18,P1413-1427
Attorney, Agent or Firm:
Asamura patent office