Title:
ＣＤ４０とＥｐＣＡＭに結合するバイスペシフィック抗体
Document Type and Number:
Japanese Patent JP7311425
Kind Code:
B2
Abstract:
The purpose of the present invention is to provide a bispecific antibody containing an antigen-binding domain which binds to CD40 and an antigen-binding domain which binds to the Epithelial Cell Adhesion Molecule (EpCAM). This invention pertains to a bispecific antibody containing an antigen-binding domain which binds to CD40 and an antigen-binding domain which binds to EpCAM.
Inventors:
Makoto Nakayama
Nobuaki Takahashi
Sayaka Maeda
Rinpei Niwa
Nobuaki Takahashi
Sayaka Maeda
Rinpei Niwa
Application Number:
JP2019552820A
Publication Date:
July 19, 2023
Filing Date:
November 06, 2018
Export Citation:
Assignee:
Kyowa Kirin Co., Ltd.
International Classes:
C12N15/13; A61K39/395; A61K49/00; A61P35/00; C07K16/28; C07K16/30; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/63; C12P21/08; G01N33/574
Foreign References:
| WO2009131239A1 | ||||
| WO2006033386A1 | ||||
| US20070238665 |
Other References:
BRUNEKREEFT,Kim L et al.,Targeted delivery of CD40L promotes restricted activation of antigen-presenting cells and induction,Molecular Cancer,2014年,vol.13:85,p.1-13
YE, Shiming et al.,Enhancement of tumor specific immunity by activation of CD40 through a bispecific molecule targeting,Journal for ImmunoTherapy of Cancer,2017年11月07日,Vol. 5 (Suppl 2): 87,p. 182: P370
YE, Shiming et al.,Enhancement of tumor specific immunity by activation of CD40 through a bispecific molecule targeting,Journal for ImmunoTherapy of Cancer,2017年11月07日,Vol. 5 (Suppl 2): 87,p. 182: P370
Attorney, Agent or Firm:
Patent Attorney Corporation Eiko Office
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