Title:
BUTENYL-SUBSTITUTED TAXANES AND COMPOSITION
Document Type and Number:
Japanese Patent JP2006257108
Kind Code:
A
Abstract:
To provide new taxane derivatives useful as antileukemia and antitumor agents.
The taxane derivatives represented by formula (3), wherein, X1 is OH; X2 is H, an alkyl, an alkenyl, an alkynyl, an aryl or a heteroaryl; X3 is H; X4 is butenyl; X5 is -COX10; X10 is an aryl, ethoxy, isopropyloxy, t-butoxy, n-butoxy, isobutoxy, neopentyloxy, cyclopropyloxy, or cyclohexyloxy.
Inventors:
HOLTON ROBERT A
CHAI KI-BYUNG
HOSSAIN NADIZADEH
CHAI KI-BYUNG
HOSSAIN NADIZADEH
Application Number:
JP2006186450A
Publication Date:
September 28, 2006
Filing Date:
July 06, 2006
Export Citation:
Assignee:
UNIV FLORIDA STATE
International Classes:
C07D205/08; A61K31/335; C07D305/14; A61K31/337; A61K31/34; A61P35/00; A61P35/02; C07C227/22; C07C229/38; C07C231/12; C07C233/87; C07C311/00; C07C323/26; C07D205/085; C07D305/10; C07D307/68; C07D407/12; C07D409/12; C07F7/10; C07F7/18; G01N27/447; C07D
Attorney, Agent or Firm:
Aoyama Aoi
Yasuo Shibata
Yasuo Shibata
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