Title:
CLUAP1ペプチドおよびそれを含むワクチン
Document Type and Number:
Japanese Patent JP2013523083
Kind Code:
A
Abstract:
Peptide vaccines against cancer are described herein. In particular, epitope peptides derived from the CLUAP1 gene that elicit CTLs are provided. Antigen-presenting cells and isolated CTLs that target such peptides, as well as methods for inducing the antigen-presenting cell, or CTL are also provided. The present invention further provides pharmaceutical compositions containing as active ingredient peptides derived from CLUAP1 or polynucleotides encoding the peptides as active ingredients. Furthermore, the present invention provides methods for the treatment and/or prophylaxis (i.e., prevention) of cancers (tumors), and/or the prevention of postoperative recurrence thereof, as well as methods for inducing CTLs, methods for inducing anti-tumor immunity, using the peptides derived from CLUAP1, polynucleotides encoding the peptides, or antigen-presenting cells presenting the peptides, or the pharmaceutical compositions of the present invention.
Inventors:
Yusuke Nakamura
Takuya Tsunoda
Ryuji Osawa
Yoshimura Sachiko
Watanabe Asahisa
Takuya Tsunoda
Ryuji Osawa
Yoshimura Sachiko
Watanabe Asahisa
Application Number:
JP2012544968A
Publication Date:
June 17, 2013
Filing Date:
October 26, 2010
Export Citation:
Assignee:
OncoTherapy Science Co., Ltd.
International Classes:
C12N15/09; A61K39/00; A61K48/00; A61P35/00; C07K7/06; C12N1/15; C12N1/19; C12N1/21; C12N5/078; C12N5/10; G01N33/53
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto