ＣＤ７を標的にするキメラ抗原受容体及びその使用

Title:

ＣＤ７を標的にするキメラ抗原受容体及びその使用

Document Type and Number:

Japanese Patent JP2023548844

Kind Code:

A

Abstract:

抗ＣＤ７抗体を含む抗原結合領域を含むキメラ抗原受容体を発現し、内因性ＣＤ７、少なくとも１種類のＴＣＲ／ＣＤ３遺伝子及び少なくとも１種類のＭＨＣクラスＩＩ関連遺伝子の発現が抑制され又はサイレンシングする改変免疫細胞を提供する。ＣＤ７発現に関する疾患の治療における前記改変免疫細胞の使用をさらに提供する。【選択図】図１

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Inventors:

Zhou Ali
Jiang Xiaoyan
Chen Gong
Ren Jiangtao
Kohiro Ga
king
Korea Russia

Application Number:

JP2023526562A

Publication Date:

November 21, 2023

Filing Date:

October 29, 2021

Export Citation:

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Assignee:

BIOHENG THERAPEUTICS LIMITED

International Classes:

C12N5/10; A61K35/15; A61K35/17; A61P35/00; A61P35/02

Attorney, Agent or Firm:

Momoko Arima

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