Title:
不斉移動水素化のための触媒として適したキラル化合物
Document Type and Number:
Japanese Patent JP2008519798
Kind Code:
A
Abstract:
The invention relates to an enantiomerically enriched chiral compound comprising a transition metal M, which comprises four, five or six coordinating groups of which at least one pair is linked together to form a bidentate ligand, in which M is directly bound via one single σ-bond to a carbon atom of an optionally substituted and/or optionally fused (hetero)aromatic ring of said bidentate ligand and in which M is directly bound to a nitrogen atom of a primary or secondary amino group of said bidentate ligand, thereby forming a metallacycle between said bidentate ligand and the metal M, said metal M being selected from the metals of groups 8 and 9 of the Periodic Table of the Elements, in particular iron, ruthenium, osmium, cobalt, rhodium, or iridium. The chiral compound can be used as a catalyst, preferably in an asymmetric transfer hydrogenation process. The invention further relates to a process for an asymmetric transfer hydrogenation of a prochiral compound in the presence of a hydrogen donor and the chiral compound of the invention comprising a transition metal chosen from the metals of groups 8, 9 and 10 of the Periodic Table, in particular iron, ruthenium, osmium, cobalt, rhodium, iridium, nickel, palladium or platinum as the catalyst.
Inventors:
Friesde, Johannes, Geralds
Feldil, Geralds, Charles, Maria
Friesde, Andreas, Hendrix, Maria
Laitren, vincent
Volclan, Adeline, Marie, Josephie
Feldil, Geralds, Charles, Maria
Friesde, Andreas, Hendrix, Maria
Laitren, vincent
Volclan, Adeline, Marie, Josephie
Application Number:
JP2007540604A
Publication Date:
June 12, 2008
Filing Date:
November 10, 2005
Export Citation:
Assignee:
DSM IP ASSETS B.V.
International Classes:
C07C211/42; C07C15/04; C07C29/143; C07C33/22; C07B53/00; C07B61/00; C07F15/00
Attorney, Agent or Firm:
Yuichi Yamada
Masakazu Noda
Yoshinori Shimizu
Masakazu Noda
Yoshinori Shimizu