COMPOSITION FOR SKIN - National University Corporation Tokyo Medical and Dental University

Title:

COMPOSITION FOR SKIN

Document Type and Number:

Japanese Patent JP2023052310

Kind Code:

A

Abstract:

To provide a method for promoting skin wound healing and a composition for use in promoting skin wound healing; to provide a method or composition useful for preventing or improving ulcers/bedsores; to provide a method for inhibiting skin aging and a composition for use in inhibiting skin aging; to provide a composition useful for preventing or improving skin disorders caused by anticancer agents, and to further provide a method for enhancing the regenerative capacity of epidermal stem cells and a composition for enhancing the regenerative capacity of epidermal stem cells.SOLUTION: By using a composition containing, as an active ingredient, a substance selected from the group consisting of a substance that induces or maintains the expression of COL17A1 in cells, a substance that suppresses degradation of COL17A1 in cells, a substance that promotes the competitive amplification of epidermal stem cells, a substance that suppresses genomic stress or oxidative stress in cells, and a substance that suppresses DNA damage in cells, promotion of skin wound healing, protection against anticancer drugs, suppression of skin aging, and enhancement of the ability to regenerate epidermal stem cells can be achieved.SELECTED DRAWING: None

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Inventors:

Nishimura Emi

Application Number:

JP2023002222A

Publication Date:

April 11, 2023

Filing Date:

January 11, 2023

Export Citation:

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Assignee:

National University Corporation Tokyo Medical and Dental University

International Classes:

A61K45/00; A23L33/10; A23L33/105; A61K8/35; A61K8/40; A61K8/49; A61K8/63; A61K8/9783; A61K8/9789; A61K31/12; A61K31/155; A61K31/352; A61K31/41; A61K31/415; A61K31/4178; A61K31/4409; A61K31/551; A61K31/567; A61K35/36; A61K36/185; A61K36/24; A61K36/27; A61K36/28; A61K36/605; A61K36/73; A61K36/82; A61K36/906; A61K38/18; A61K48/00; A61P17/02; A61P17/16; A61P17/18; A61P39/06; A61P43/00; A61Q19/00; A61Q19/08; C12N5/071; C12Q1/02; C12Q1/6851; C12Q1/6881; G01N33/15; G01N33/50; G01N33/53

Attorney, Agent or Firm:

Katsuhiro Ito
Shinichi Watanabe

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