Title:
COMPOSITIONS AND METHODS FOR TREATING CANCER WITH ATYPICAL BRAF MUTATIONS
Document Type and Number:
Japanese Patent JP2022176316
Kind Code:
A
Abstract:
To provide methods, pharmaceutical compositions and kits for treating or ameliorating the effects of a cancer in a subject which harbors an atypical BRAF mutation (i.e., a non-V600E/K BRAF mutation), comprising an ERK inhibitor.SOLUTION: Also provided are methods for identifying a subject having an atypical BRAF mutant cancer expected to benefit from therapy including an ERK inhibitor. In one aspect, the ERK inhibitor is BVD-523.SELECTED DRAWING: None
Inventors:
Gary Decresenzo
Dean Welsh
Saurabh Saha
Dean Welsh
Saurabh Saha
Application Number:
JP2022160828A
Publication Date:
November 25, 2022
Filing Date:
October 05, 2022
Export Citation:
Assignee:
Biomed Valley Discoveries, Incorporated
International Classes:
A61K45/00; A61K9/08; A61K9/20; A61K31/437; A61K31/4439; A61K31/444; A61K35/74; A61K38/19; A61K38/20; A61K38/21; A61K38/22; A61K39/395; A61K47/12; A61K47/22; A61K47/68; A61K51/00; A61P35/00; A61P37/02; A61P43/00; C12N9/99
Attorney, Agent or Firm:
Shusaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto