Title:
Covering unjust change resistance controlled release dosage forms
Document Type and Number:
Japanese Patent JP6232025
Kind Code:
B2
Abstract:
In certain embodiments, the present invention is directed to a solid controlled release dosage form comprising: a therapeutically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof dispersed in a controlled release excipient; wherein the inner 50% of the dosage form contains at least 80% of the hydrocodone or salt thereof; wherein the amount of hydrocodone or salt thereof released from the dosage form is proportional within 20% to elapsed time from 8 to 24 hours, as measured by an in-vitro dissolution in a USP Apparatus 1 (basket) at 100 rpm in 900 ml simulated gastric fluid without enzymes (SGF) at 37°C.
Inventors:
Fan, hyeon, hugh
Application Number:
JP2015203529A
Publication Date:
November 15, 2017
Filing Date:
October 15, 2015
Export Citation:
Assignee:
PURDUE PHARMA L.P.
International Classes:
A61K9/22; A61K31/485; A61K47/32; A61P25/04; A61P25/36
Domestic Patent References:
| JP2010501543A | ||||
| JP2003521507A |
Foreign References:
| US20040241234 |
Other References:
永井恒司,新・ドラッグデリバリーシステム,株式会社シーエムシー,2000年,p.11-18
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Kyoei Sugiyama
Yasuhito Suzuki
Norio Omori
Kyoei Sugiyama
Yasuhito Suzuki
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