Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
CYCLOPROPACHROMENE DERIVATIVE
Document Type and Number:
Japanese Patent JPH04235180
Kind Code:
A
Abstract:

PURPOSE: To obtain a new cyclopropachromene useful as an improving agent and a treating agent for symptoms based on organizing and functional disorder in the brain, a psychotropic agent, etc.

CONSTITUTION: A compound shown by formula I (n is 2-5 integer; R1 and R2 are H, 1-5C alkyl, phenyl, etc., or R' and R" together with N form morpholino, thiomorpholino, pyrrolidinyl, piperidinyl, pyrrolizidinyl, etc.; A1, R2, B1 and B2 are H, halogen, OH, alkoxy, etc.) and a pharmaceutically acceptable salt thereof such as 1a,7a-dihydro-4,5-dimethoxy-7(1H)-(2-methylaminoethyloxyimino)-1 a-phenylcyclopropa[b]chromene. The compound is obtained by reacting a compound shown by formula II hydroxyamine hydrochloride in pyridine to give a compound shown by formula III and condensing this compound with an amino halide shown by formula IV (X is halogen).


Inventors:
TATSUOKA TOSHIO
NOMURA KAYOKO
Application Number:
JP3292291A
Publication Date:
August 24, 1992
Filing Date:
February 27, 1991
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
SUNTORY LTD
International Classes:
A61K31/352; A61P25/18; A61K31/35; A61P25/28; C07D311/94; (IPC1-7): A61K31/35; C07D311/94
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)