Title:
DFMOのD-鏡像異性体およびその癌を処置するための使用方法
Document Type and Number:
Japanese Patent JP2004504271
Kind Code:
A
Abstract:
The present invention concerns a method for preventing and/or treating cancer in a patient comprising administering an effective amount of substantially purified D enantiomer of difluoromethylornithine (D-DFMO) or an analog of D-DFMO to the patient. D-DFMO or an analog thereof is administered at a dose of about 0.05 to about 20.0 gm/M2/day. D-DFMO or an analog thereof may be administered more than once for the treatment and/or prevention of cancer. Methods of administration as well as compositions and formulations of substantially purified D-DFMO and analogs of D-DFMO are described.
Inventors:
Levenson, Collie
Shake, Jive
Shake, Jive
Application Number:
JP2001566640A
Publication Date:
February 12, 2004
Filing Date:
March 07, 2001
Export Citation:
Assignee:
ILEX ONCOLOGY, INC.
International Classes:
A61K9/02; A61K9/06; A61K9/08; A61K9/10; A61K9/14; A61K9/20; A61K9/48; A61K31/00; A61K31/195; A61K31/198; A61P35/00; A61P43/00; (IPC1-7): A61K31/198; A61K9/02; A61K9/06; A61K9/08; A61K9/10; A61K9/14; A61K9/20; A61K9/48; A61P35/00; A61P43/00
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita