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Title:
齲蝕細菌検出用DNAチップ
Document Type and Number:
Japanese Patent JP6959021
Kind Code:
B2
Abstract:
Provided is a means/method with which it is possible to quickly and efficiently detect bacteria that cause dental caries and evaluate dental caries. The present invention pertains to a DNA chip, etc., that carries, for example, the following probe (a) and at least one probe from among the following probes (b) and (c). (a) A probe comprising a nucleic acid that hybridizes to 16S rRNA specific to each of one or more oral bacteria to be detected, wherein the probe is any of the following sequences (i)-(iii): (i) at least one sequence selected from nucleotide sequences represented by SEQ ID NOS: 2-7; (ii) a complementary sequence of a sequence of (i); or (iii) a sequence substantially identical to a sequence of (i) or (ii). (b) A total amount indicator probe. (c) An absolute amount indicator probe of one type or a plurality of types.

Inventors:
Ai Hara
Takayama Kazuto
Application Number:
JP2017048654A
Publication Date:
November 02, 2021
Filing Date:
March 14, 2017
Export Citation:
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Assignee:
GC Corporation
International Classes:
C12Q1/689; C12M1/00; C12N15/09; G01N33/50; G01N33/53; G01N33/569; G01N37/00
Domestic Patent References:
JP2008206516A
JP2015231362A
JP2017023093A
Foreign References:
WO2003106676A1
WO2016129249A1
Other References:
GROSS, Erin L. et al.,PLOS ONE,2012年,Vol. 7, Issue 10,e47722, doi:10.1371/journal.pone.0047722,p. 6右欄
PONTIGO, F. et al.,Genetics and Molecular Research,2015年,Vol. 14, No. 3,p. 10905-10918,table 1
GROSS, Erin L. et al.,Beyond Streptococcus mutans:,PLOS ONE,2012年,Vol. 7, Issue 10,e47722, doi:10.1371/journal.pone.0047722,p. 6右欄
PONTIGO, F. et al.,Molecular phylogeny and a taxonomic proposal for the genus Streptococcus,Genetics and Molecular Research,2015年,Vol. 14, No. 3,p. 10905-10918,table 1
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Koichi Iwata
Yasuhito Suzuki