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Title:
タンデム質量分析によるキスペプチン−54の検出
Document Type and Number:
Japanese Patent JP6444736
Kind Code:
B2
Abstract:
Methods are described for measuring the amount of a kisspeptin-54-derived peptides in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying a kisspeptin-54 derived peptides in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric techniques.

Inventors:
Bistro, collie
Rights, richard
Application Number:
JP2014543542A
Publication Date:
December 26, 2018
Filing Date:
November 20, 2012
Export Citation:
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Assignee:
Quest Diagnostics Investments Inc.
International Classes:
G01N27/62; G01N33/68
Domestic Patent References:
JP2010197110A
Foreign References:
WO2011128357A2
WO2007055362A1
Other References:
“metastasis-supressor KiSS-1 preproprotein [Homo sapiens] - Protein - NCBI”, NCBI [online], Accession: NP_002247.3, 2011年10月8日 [2016年8月17日検索],インターネット
HORIKOSHI,Y. 外6名,“Dramatic Elevation of Plasma Metastin Concentrations in Human Pregnancy: Metastin as a Novel Placenta-Derived Hormone in Humans”, THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, Volume 88, Issue 2, 2003年, Pages 914-919
富田健嗣,外4名,“GPR54アゴニストの構造活性相関研究”,第34回構造活性相関シンポジウム,2006年, Article K03, 4 Pages
ANDERSON,N.L. 外5名,“Mass Spectrometric Quantitation of Peptides and Proteins Using Stable Isotope Standards and Capture by Anti-Petide Antibodies(SISCAPA)”, JOURNAL OF PROTEOME RESEARCH, Volume 3, Number 2, 2004年6月22日, Pages 235-244
Attorney, Agent or Firm:
Seiji Ohno
Yuko Matsuniya
Umeda Shinsuke
Hiroshi Morita