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Title:
卵アレルギーの抗原
Document Type and Number:
Japanese Patent JP6381093
Kind Code:
B2
Abstract:
The present invention provides novel antigens of an allergy to egg, methods and kits for diagnosing an allergy to egg, pharmaceutical compositions comprising such an antigen, eggs or processed products of egg in which such an antigen is eliminated or reduced, birds that deliver such eggs or are born from such eggs, a method for producing processed products of egg in which such an antigen is eliminated or reduced, and a tester for determining the presence or absence of an egg antigen in an object of interest. The present invention also relates to polypeptides comprising an epitope of an antigen, kits, compositions and methods for diagnosing an allergy, comprising such a polypeptide, pharmaceutical compositions comprising such a polypeptide, and raw materials or processed products in which an antigen comprising such a polypeptide is eliminated or reduced. The present invention further relates to a tester for determining the presence or absence of an antigen in an object of interest.

Inventors:
Kayoko Matsunaga
Yagami Akiko
Nakamura Masashi
Yuji Aoki
Kondo Erika
Application Number:
JP2017541714A
Publication Date:
August 29, 2018
Filing Date:
June 02, 2017
Export Citation:
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Assignee:
Fujita Gakuen
Hoyu Co., Ltd.
International Classes:
G01N33/53; A01K67/027; A23L15/00; A23L33/17; A61K39/35; A61P37/08; C07K14/465
Domestic Patent References:
JP5894695B2
JP2014525745A
JP2016141666A
Foreign References:
US20060205823
US20100210033
Other References:
AMO Alvaro,Gal d 6 Is the Second Allergen Characterized from Egg Yolk,J Agric Food Chem,2010年 6月23日,Vol.58 No.12,Page.7453-7457
HUGHES, Austin L,Life-history evolution at the molecular level: adaptive amino acid composition of avian vitellogenin,Proceedings of the Royal Society Biological Sciences Series B,2015年 8月 7日,Vol.282, No.1812,Page.76-82
PREDICTED: vitellogenin-3 [Gallus gallus],NCBI > Proteins > Protein Database,2016年 1月 4日,Accession no. XP_015146355.1,[オンライン][検索日 2017.08.10],URL,https://www.ncbi.nlm.nih.gov/protein/971408444
SILVA, R,The major and minor chicken vitellogenin genes are each adjacent to partially deleted pseudogene cop,Mol Cell Biol,1989年 8月,Vol.9 No.8,Page.3557-3562
HILDEBRANDT Sabine,In Vitro Determination of the Allergenic Potential of Technologically Altered Hen's Egg,J Agric Food Chem,2008年 3月12日,Vol.56 No.5,Page.1727-1733
民谷栄一,バイオセンサーチップと抗体エンジニアリング,バイオインダストリー,2003年 7月12日,Vol.20 No.7,Page.60-67
Attorney, Agent or Firm:
Shinjiro Ono
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi
Hirose Shinobu