EPIDURAL ADMINISTRATION OF THERAPEUTIC COMPOUNDS WITH SUSTAINED RATE OF RELEASE

Title:

EPIDURAL ADMINISTRATION OF THERAPEUTIC COMPOUNDS WITH SUSTAINED RATE OF RELEASE

Document Type and Number:

Japanese Patent JP2010043104

Kind Code:

A

Abstract:

To provide a drug for sustained release delivery of a physiologically active therapeutic compound administered epidurally.

A liposome preparation for treating the pain after surgery of a vertebrate animal or after delivery is epidurally administered as a single dose and includes an analgetic compound or an anesthetic compound encapsulated within multi-vesicular liposomes formed of phospholipids such as dipalmitoyl phosphatidyl choline, and dioleoyl phosphatidyl choline, and steroids such as cholesterol. The analgetic compound or the anesthetic compound is sustainedly released.

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Inventors:

KIM SINIL
MURDANDE SHARAD B
GRUBER ANDRAS
KIM TAEHEE

Application Number:

JP2009230419A

Publication Date:

February 25, 2010

Filing Date:

October 02, 2009

Export Citation:

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Assignee:

PACIRA PHARMACEUTICALS INC

International Classes:

A61K9/127; A61M31/00; A61K9/00; A61K9/12; A61K31/485; A61K47/24; A61K47/28; A61P25/04

Domestic Patent References:

JPH01125318A	1989-05-17
JPS62181225A	1987-08-08
JP2008013960A	2008-01-24
JPH11508990A	1999-08-03

Foreign References:

WO1994023697A1	1994-10-27
WO1995013796A1	1995-05-26

Attorney, Agent or Firm:

Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Eiichi Arai
Ai Fujii

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