Title:
EXTERNAL AGENT FOR SUPPRESSING MELANOGENESIS
Document Type and Number:
Japanese Patent JP3435181
Kind Code:
B2
Abstract:
PURPOSE: To obtain a melanogenesis-suppressing external agent containing a liquid obtained by culturing yeast in a sugar syrup or a cultured extract, exhibiting remarkably excellent melanogenesis-suppressing effect and humectant effect and useful also as an active component for skin-beautifying cosmetic required to give moist feeling to the skin.
CONSTITUTION: A yeast belonging to the genus Saccharomyces is cultured in a sugar syrup (especially a medium derived from barley) and the obtained cultured yeast liquid or extract of the cultured liquid is used as an active component for the objective melanogenesis-suppressing external agent. The sugar syrup to be used as a medium is preferably produced by heating and dilating barley, wheat, rye, oat, etc., optionally in the presence of water and treating the product with saccharifying enzyme to increase the production of the melanogenesis-suppressing substance by yeast. Saccharification is performed in high efficiency by adding an α-amylase in combination with a glucoamylase as the saccharification enzymes. The amount of the cultured liquid or culture extract in the preparation is preferably 0.1-10wt.%. The external agent can be used in the form of poultice, plaster, paste, cream, ointment, aerosol, sun-care, bath-salt, soap, etc.
Inventors:
Takahiro Saegusa
Application Number:
JP634393A
Publication Date:
August 11, 2003
Filing Date:
January 19, 1993
Export Citation:
Assignee:
Sansho Pharmaceutical Co., Ltd.
International Classes:
A61K8/96; A61K8/00; A61K8/99; A61K36/06; A61K38/00; A61P17/00; A61Q17/04; A61Q19/00; A61Q19/02; (IPC1-7): A61K7/48; A61K7/00; A61K7/42; A61K35/72; A61K38/00; A61P17/00
Domestic Patent References:
| JP5636419A | ||||
| JP61260009A | ||||
| JP61172812A | ||||
| JP61118322A |
Other References:
フレグランス ジャーナル，１９９２年，第２０巻，第３号，ｐｐ．１８−２１
Attorney, Agent or Firm:
Yukio Shoko (1 person outside)