Title:
蛍光媒介式分子断層撮影法
Document Type and Number:
Japanese Patent JP5134977
Kind Code:
B2
Abstract:
This invention relates to a fluorescence-mediated molecular tomographic imaging system, designed to detect near-infrared fluorescence activation in deep tissues. The system can use targeted fluorescent molecular probes orhighly sensitive activatable fluorescence molecular probes. Such probes add molecular specificity and yield high fluorescence contrast, to allow early detection and molecular target assessment of diseased tissue, such as cancers, in vivo. The new tomographic imaging system enables three-dimensional localization in deep tissues and quantitation of molecular probes.
Inventors:
Nizia Christos Basilis
Weiss Radar Ralph
Weiss Radar Ralph
Application Number:
JP2008004715A
Publication Date:
January 30, 2013
Filing Date:
January 11, 2008
Export Citation:
Assignee:
The General Hospital Corporation
International Classes:
G01N21/64; A61B5/00; A61B6/00; A61B10/00; A61K49/08; G01N21/00; G01N21/17; G01N21/47
Domestic Patent References:
| JP5223738A | ||||
| JP4122248A | ||||
| JP8131445A | ||||
| JP11173976A | ||||
| JP10508763A | ||||
| JP2001521147A | ||||
| JP2002502653A | ||||
| JP2002528714A | ||||
| JP2002523731A | ||||
| JP2000500228A | ||||
| JP4083149A | ||||
| JP10206742A | ||||
| JP62180241A |
Foreign References:
| WO1999020997A1 | ||||
| WO1999040841A1 | ||||
| WO2000025113A1 | ||||
| WO2000011024A2 |
Attorney, Agent or Firm:
Hatsushi Shimizu