Title:
縮環ラクタム誘導体
Document Type and Number:
Japanese Patent JP2024020396
Kind Code:
A
Abstract:
【課題】セロトニン５－ＨＴ２Ａ受容体に対するアンタゴニスト活性およびセロトニン５－ＨＴ１Ａ受容体に対するアゴニスト活性を併せ持つ精神神経疾患の治療剤の提供。【解決手段】式（１）の化合物。TIFF2024020396000176.tif5180（Ｖ：ＣＲＡＲＢ。ｎ：１、２。Ｚ：Ｎ、Ｃなど。ｔ：１～３。結合（ａ）：単結合、二重結合。ＲＡ、ＲＢ：Ｈ、Ｃ１－６アルキルなど。Ｒ１ａ～Ｒ１ｄ：Ｈ、ハロゲンなど。Ｑ１：置換／非置換５員または６員芳香族複素間を含む縮合複素環。Ｑ２：置換／非置換ベンゾ－１，２－オキサゾールまたはベンゾ－１，２－チアゾール）【選択図】なし
Inventors:
Hidefumi Yoshinaga
Yohei Ikuma
Junya Ikeda
Satoshi Adachi
Harunobu Minuma
Yoshinori Aihara
Jeremy Besnaldo
Andrew Simon Bell
Yohei Ikuma
Junya Ikeda
Satoshi Adachi
Harunobu Minuma
Yoshinori Aihara
Jeremy Besnaldo
Andrew Simon Bell
Application Number:
JP2023194068A
Publication Date:
February 14, 2024
Filing Date:
November 15, 2023
Export Citation:
Assignee:
Sumitomo Pharma Co., Ltd.
International Classes:
C07D413/12; A61K31/454; A61K31/4545; A61K31/496; A61K31/519; A61K31/55; A61K45/00; A61P15/10; A61P25/00; A61P25/16; A61P25/18; A61P25/20; A61P25/24; A61P25/28; A61P43/00; C07D413/14; C07D417/12; C07D471/04; C07D487/04; C07D491/048; C07D495/04; C07D498/04
Attorney, Agent or Firm:
Norito Yamao
Nagatoshi Shinagawa
Wu Yingyan
Masahiro Suwon
Nagatoshi Shinagawa
Wu Yingyan
Masahiro Suwon
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