FUSED PROTEIN HAVING EUKARYOTIC BALLAST PART

Title:

FUSED PROTEIN HAVING EUKARYOTIC BALLAST PART

Document Type and Number:

Japanese Patent JPS62167799

Kind Code:

A

Abstract:

Suitable as "ballast portion" for fusion proteins is a part of the amino-acid sequence of interleukin-2 (IL-2) which comprises considerably less than 100 amino acids. It is advantageous to start from a synthetic IL-2 gene which is divided by unique cleavage sites into six segments of which up to three can be linked in any desired sequence by the building block principle. Specific constructions allowing the solubility of the fusion protein to be varied are possible.

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Inventors:

HABERMANN PAUL (DE)

Application Number:

JP30618586A

Publication Date:

July 24, 1987

Filing Date:

December 22, 1986

Export Citation:

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Assignee:

HOECHST AG

International Classes:

A61K35/74; A61K38/00; A61P37/00; C07H21/04; C07K14/00; C07K14/52; C07K14/535; C12N15/09; C07K14/54; C07K14/55; C07K14/62; C07K14/815; C07K19/00; C12N1/20; C12N1/21; C12N15/00; C12N15/26; C12P21/02; C12R1/19; C12R1/645; (IPC1-7): A61K35/74; A61K37/02; C07K13/00; C12N1/20; C12N15/00; C12P21/02; C12R1/19

Attorney, Agent or Firm:

Kazuo Sato

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