Title:
慢性関節リウマチに関連する遺伝的多型、その検出方法および使用
Document Type and Number:
Japanese Patent JP2006521812
Kind Code:
A
Abstract:
The present invention is based on the discovery of genetic polymorphisms that are associated with rheumatoid arthritis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
Inventors:
Alexander and Heather See.
Cargill and Mitchell
ビゴビック and Ann B.
Cargill and Mitchell
ビゴビック and Ann B.
Application Number:
JP2006507374A
Publication Date:
September 28, 2006
Filing Date:
March 18, 2004
Export Citation:
Assignee:
アプレラ Condominium ration
International Classes:
C12N15/09; C07K14/47; C07K16/18; C12Q1/68; G01N33/15; G01N33/50; C12P21/08
Domestic Patent References:
| JP2002537774A | 2002-11-12 | |||
| JP2002528096A | 2002-09-03 | |||
| JP2002537774A | 2002-11-12 | |||
| JP2002528096A | 2002-09-03 |
Foreign References:
| WO2002050307A1 | 2002-06-27 | |||
| WO2001011084A1 | 2001-02-15 | |||
| WO2002074989A2 | 2002-09-26 | |||
| WO2002050307A1 | 2002-06-27 | |||
| WO2001011084A1 | 2001-02-15 | |||
| WO2002074989A2 | 2002-09-26 |
Other References:
JPN6009061894, Ａｍ． Ｊ． Ｈｕｍ． Ｇｅｎｅｔ．, 2001, Ｖｏｌ． ６８, ｐｐ．６７４−６８５
Attorney, Agent or Firm:
Takaaki Yasumura
Shusaku Yamamoto
Natsuki Morishita
Shusaku Yamamoto
Natsuki Morishita