GENETICALLY MODIFIED MICRO ORGAN EXPLANT, METHOD FOR PRODUCING THE SAME AND ITS APPLICATION

Title:

GENETICALLY MODIFIED MICRO ORGAN EXPLANT, METHOD FOR PRODUCING THE SAME AND ITS APPLICATION

Document Type and Number:

Japanese Patent JP2004073206

Kind Code:

A

Abstract:

To provide a method for inducing vascularization in mammal organization.

The genetically modified micro organ explant manifests at least one recombinant DNA product, wherein the micro organ explant contains a cell group and keeps a microstructure and a three-dimensional structure of the original organ and has a size selected to minimize death caused by cytotoxicity, excrement accumulation and insufficient nutrient by diffusing sufficient nutrients and gas into cells in the micro organ explant and diffusing cell excrements from the micro organ explant, and some cells of the group of the micro organ explant cell manifest micro organ explant expresses at least one recombinant gene product.

Inventors:

MITRANI EDUARDO N

Application Number:

JP2003305960A

Publication Date:

March 11, 2004

Filing Date:

August 29, 2003

Export Citation:

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Assignee:

YISSUM RES DEV CO

International Classes:

A61K35/12; A61K35/26; A61K35/28; A61K35/34; A61K35/36; A61K35/37; A61K35/39; A61K35/407; A61K35/42; A61K35/44; A61K35/48; A61K48/00; A61L27/38; A61P1/18; A61P7/00; A61P9/00; A61K35/23; A61P17/00; A61P27/02; A61P35/00; A61P43/00; C12N5/00; C12N5/08; C12N5/10; C12N15/09; C12N15/85; (IPC1-7): C12N15/09; A61K35/12; A61K35/23; A61K35/26; A61K35/36; A61K35/37; A61K35/39; A61K35/407; A61K35/42; A61K35/44; A61K35/48; A61P1/18; A61P17/00; A61P27/02; A61P43/00; C12N5/10

Attorney, Agent or Firm:

Nobuaki Kazehaya

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