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Title:
GINGIVAL HYPERTROPHY INHIBITOR
Document Type and Number:
Japanese Patent JP2002212101
Kind Code:
A
Abstract:

To provide an excellent gingival hypertrophy inhibitor.

This gingival hypertrophy inhibitor contains a compound having angiotensin II antagonism, its prodrug or its salt. The compound having the angiotensin II antagonism preferably comprises a compound expressed by formula (I) [R1 is an anion-formable group or a group which can be changed into the anion-formable group; X is a linkage which joins the phenylene and the phenyl directly or through a spacer comprising two or less atomic chains; A is a benzene ring which may be further substituted; R2 is an anion-formable group or a group which can be changed into the anion-formable group; R3 is a hydrocarbon residue which may be bonded through a hetero atom or may be substituted; and n is 1 or 2] and more preferably comprises Losartan, Eprosartan, Candesartan cilexetil, Candesartan, Valsartan, Telmisartan, Irbesartan, Olmesartan or Tasosartan.


Inventors:
MURAKAMI HAJIME
Application Number:
JP2001011650A
Publication Date:
July 31, 2002
Filing Date:
January 19, 2001
Export Citation:
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Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD
International Classes:
A61K31/41; A61K31/4178; A61K31/4184; A61K31/4245; A61K31/496; A61K31/522; A61K45/00; A61P1/02; A61P43/00; C07D257/04; C07D403/10; C07D409/06; C07D413/10; C07D471/04; C07D235/20; (IPC1-7): A61K45/00; A61K31/41; A61K31/4178; A61K31/4184; A61K31/4245; A61K31/522; A61P1/02; A61P43/00
Attorney, Agent or Firm:
Sekiguchi Yo (1 person outside)