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Title:
GLUCOSAMINE DERIVATIVE
Document Type and Number:
Japanese Patent JPS5815992
Kind Code:
A
Abstract:

NEW MATERIAL:A compound shown by the formulaI(R is ≤6C organic acid residue; n is 14W20; R1 is H or lower alkyl; R2 and R3 are H or lower alkyl which may be replaced with OH; R4 is H or lower alkyl; R5 is carboxyl which may be esterified or amidated; D and L are in steric configuration when carbon atom is asymmetric) or its salt.

EXAMPLE: 2-[2-Acetamide-2-deoxy-6-0-{2-[10-(2, 3-dimethoxy-5-methyl-1,4-benzoquinone-6-yl)decanyl]-3-hydroxytetracosanoyl}-D-glucopyranose-3-0-yl]-D-propionyl-L-alanyl-D-isoglutamine.

USE: An immune function enhancer.

PROCESS: A compound shown by the formula II (R6 and R7 OH which may be protected) is condensed with a compound shown by the formula III (R2' and R3' are OH, etc.; R5' is protected carboxyl, etc.) and deprotected, to give a compound shown by the formulaI.


Inventors:
YAMAMURA YUUICHI
AZUMA ICHIROU
KOBAYASHI SAKAE
Application Number:
JP11572281A
Publication Date:
January 29, 1983
Filing Date:
July 22, 1981
Export Citation:
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Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD
International Classes:
C07K9/00; A61K31/70; A61P37/04; C07H15/04; (IPC1-7): A61K31/70; C07H15/04
Attorney, Agent or Firm:
Hiroshi Iwata



 
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