Rafキナーゼ阻害剤として有用なヘテロアリール化合物

Japanese Patent JP2012514044

A

The present invention provides compounds of formula (I) useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.

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Chuaqui, Claudio
Coslow, jennifer
Dowling, james
Guan, Bin
Homan, Michael
Ishchenko, Alexei
Jones, John Howard
Cavitating, loli
Bear Label, Gunana Sambang Dam
Pen, hiluo
Powell, Noel
Raimund, Bryan
Yuko Tanaka
Van broten, cart
Bethels, Jeffrey
Shin, Chili

JP2011544601A

June 21, 2012

December 30, 2009

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MILLENNIUM PHARMACEUTICALS, INC.

C07D261/18; A61K31/42; A61K31/427; A61K31/428; A61K31/437; A61K31/4439; A61K31/444; A61K31/4545; A61K31/4709; A61K31/496; A61K31/497; A61K31/498; A61K31/4985; A61K31/5025; A61K31/519; A61K31/52; A61K31/53; A61K31/5377; A61K31/538; A61K31/55; A61K31/551; A61K45/00; A61P1/04; A61P1/18; A61P9/00; A61P11/00; A61P13/02; A61P13/08; A61P13/10; A61P13/12; A61P15/00; A61P17/00; A61P19/00; A61P25/00; A61P25/28; A61P29/00; A61P31/12; A61P35/00; A61P35/02; A61P37/06; A61P43/00; C07D277/62; C07D409/12; C07D413/12; C07D417/12; C07D417/14; C07D471/04; C07D487/04; C07D513/04

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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